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GCSE/Combined Science/Edexcel

CB8.2The circulatory system: heart structure and function, blood vessels (arteries, veins, capillaries), blood components and their roles

Notes

CB8.2 — The circulatory system (Edexcel 1SC0)

Double circulation

Humans have a double circulatory system:

  • Pulmonary circulation: right side of heart → lungs → left side of heart.
  • Systemic circulation: left side of heart → body → right side of heart.

Advantage: blood is re-oxygenated and repressurised between circuits → efficient delivery to body tissues.

Heart structure

  • Right atrium → receives deoxygenated blood from body.
  • Right ventricle → pumps blood to lungs.
  • Left atrium → receives oxygenated blood from lungs.
  • Left ventricle → pumps blood to body (thickest wall — high pressure needed).
  • Valves (atrioventricular and semilunar) → prevent backflow.

Coronary arteries supply the heart muscle itself with oxygenated blood.

Blood vessels

VesselWallLumenFunction
ArteryThick, elastic, muscularNarrowCarry blood away from heart at high pressure
VeinThin wallWideReturn blood to heart at low pressure; have valves
CapillaryOne cell thickTinyExchange of substances with tissues

Blood components

ComponentFunction
Red blood cellsCarry oxygen (haemoglobin)
White blood cellsImmune response (phagocytes, lymphocytes)
PlateletsBlood clotting
PlasmaCarries dissolved substances (glucose, CO₂, urea, hormones)

AI-generated · claude-opus-4-7 · v3-edexcel-combined-science

Practice questions

Try each before peeking at the worked solution.

  1. Question 13 marks

    Double circulation — advantage

    (3 marks) Explain one advantage of the double circulatory system over a single circulatory system.

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    AI-generated · claude-opus-4-7 · v3-edexcel-combined-science

  2. Question 24 marks

    Blood vessel comparison

    (4 marks) Compare the structure of arteries and veins. Give two structural differences and relate each to function.

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    AI-generated · claude-opus-4-7 · v3-edexcel-combined-science

  3. Question 34 marks

    Blood components

    (4 marks) Name the blood component responsible for each function:

    (a) Carrying oxygen from the lungs to the body. (1 mark)
    (b) Engulfing and destroying bacteria. (1 mark)
    (c) Carrying dissolved glucose to cells. (1 mark)
    (d) Forming a clot at the site of a wound. (1 mark)

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    AI-generated · claude-opus-4-7 · v3-edexcel-combined-science

Flashcards

CB8.2 — The circulatory system: heart, blood vessels and blood

6-card SR deck for Edexcel Combined Science topic CB8.2

6 cards · spaced repetition (SM-2)