CB8.2 — The circulatory system (Edexcel 1SC0)
Double circulation
Humans have a double circulatory system:
- Pulmonary circulation: right side of heart → lungs → left side of heart.
- Systemic circulation: left side of heart → body → right side of heart.
Advantage: blood is re-oxygenated and repressurised between circuits → efficient delivery to body tissues.
Heart structure
- Right atrium → receives deoxygenated blood from body.
- Right ventricle → pumps blood to lungs.
- Left atrium → receives oxygenated blood from lungs.
- Left ventricle → pumps blood to body (thickest wall — high pressure needed).
- Valves (atrioventricular and semilunar) → prevent backflow.
Coronary arteries supply the heart muscle itself with oxygenated blood.
Blood vessels
| Vessel | Wall | Lumen | Function |
|---|---|---|---|
| Artery | Thick, elastic, muscular | Narrow | Carry blood away from heart at high pressure |
| Vein | Thin wall | Wide | Return blood to heart at low pressure; have valves |
| Capillary | One cell thick | Tiny | Exchange of substances with tissues |
Blood components
| Component | Function |
|---|---|
| Red blood cells | Carry oxygen (haemoglobin) |
| White blood cells | Immune response (phagocytes, lymphocytes) |
| Platelets | Blood clotting |
| Plasma | Carries dissolved substances (glucose, CO₂, urea, hormones) |
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