- C1Particles — atoms, elements, compounds, kinetic theory, states of matter
- C2Elements, compounds and mixtures — atomic structure, periodic table trends, separation techniques
- C3Chemical reactions — balanced equations, types of reaction, conservation of mass
- C4Predicting and identifying reactions and products — reactivity, neutralisation, electrolysis, qualitative analysis
- C5Monitoring and controlling chemical reactions — rates of reaction, energy changes, reversible reactions, equilibrium
- C6Global challenges — atmosphere, climate change, resources, polymers, organic chemistry, fuels